Vol 9: BM-1197: A Novel and Specific Bcl-2-Bcl-xL Inhibitor Inducing Complete and Long-Lasting Tumor Regression In Vivo.Reportar como inadecuado



 Vol 9: BM-1197: A Novel and Specific Bcl-2-Bcl-xL Inhibitor Inducing Complete and Long-Lasting Tumor Regression In Vivo.


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This article is from PLoS ONE, volume 9.AbstractBcl-2 and Bcl-xL are critical regulators of apoptosis that are overexpressed in a variety of human cancers and pharmacological inhibition of Bcl-2 and Bcl-xL represents a promising strategy for cancer treatment. Using a structure-based design approach, we have designed BM-1197 as a potent and efficaci

Autor: Bai, Longchuan; Chen, Jianfang; McEachern, Donna; Liu, Liu; Zhou, Haibin; Aguilar, Angelo; Wang, Shaomeng

Fuente: https://archive.org/







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