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 Vol 9: Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease.


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This article is from PLoS ONE, volume 9.AbstractWe hypothesize that the phenomenon of allele-specific methylation (ASM) may underlie the phenotypic effects of multiple variants identified by Genome-Wide Association studies (GWAS). We evaluate ASM in a human population and document its genome-wide patterns in an initial screen at up to 380,678 sites

Autor: Hutchinson, John N.; Raj, Towfique; Fagerness, Jes; Stahl, Eli; Viloria, Fernando T.; Gimelbrant, Alexander; Seddon, Johanna; Daly, Mark; Chess, Andre

Fuente: https://archive.org/







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