Vol 13: A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling.Reportar como inadecuado



 Vol 13: A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling.


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This article is from Molecular Cancer, volume 13.AbstractBackground: High androgen receptor (AR) level in primary tumour predicts increased prostate cancer (PCa)-specific mortality. Furthermore, activations of the AR, PI3K, mTOR, NFκB and Hedgehog (Hh) signaling pathways are involved in the fatal development of castration-resistant prostate cancer

Autor: Kohler, Andrea; Demir, Ummuhan; Kickstein, Eva; Krauss, Sybille; Aigner, Johanna; Aranda-Orgilles, Beatriz; Karagiannidis, Antonios I; Achmuller, Clem

Fuente: https://archive.org/







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