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 Vol 9: A New Genotype Imputation Method with Tolerance to High Missing Rate and Rare Variants.


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This article is from PLoS ONE, volume 9.AbstractWe report a novel algorithm, iBLUP, to impute missing genotypes by simultaneously and comprehensively using identity by descent and linkage disequilibrium information. The simulation studies showed that the algorithm exhibited drastically tolerance to high missing rate, especially for rare variants th

Autor: Yang, Yumei; Wang, Qishan; Chen, Qiang; Liao, Rongrong; Zhang, Xiangzhe; Yang, Hongjie; Zheng, Youmin; Zhang, Zhiwu; Pan, Yuchun

Fuente: https://archive.org/







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