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Published in: Biomech Model Mechanobiol, vol. 1, num. 4, p. 239-49 Publication date: 2003

A model of tissue differentiation at the bone-implant interface is proposed. The basic hypothesis of the model is that the mechanical environment determines the tissue differentiation. The stimulus chosen is related to the bone-implant micromotions. Equations governing the evolution of the interfacial tissue are proposed and combined with a finite element code to determine the evolution of the fibrous tissue around prostheses. The model is applied to the case of an idealized hip prosthesis.

Keywords: *Bone Remodeling ; Computer Simulation ; Prosthesis Failure ; Stress ; Mechanical Note: LRO, Bat. AAB, Laboratory of Orthopedic Research, EPFL, 1015 Lausanne, Switzerland. philippe.buechler[at], 1617-7959 (Print), Evaluation Studies, Journal Article Reference LBO-ARTICLE-2003-001doi:10.1007/s10237-002-0024-x

Autor: Buchler, P.; Pioletti, Dominique P.; Rakotomanana, L. R.


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