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Abstract: We discuss two different ways of chromosomes- and genomes- evolution.Purifying selection dominates in large panmictic populations, where Mendelianlaw of independent gene assortment is valid. If the populations are small,recombination processes are not effective enough to ensure an independentassortment of linked genes and larger clusters of genes could be inherited asthe genetic units. There are whole clusters of genes which tend to complementin such conditions instead of single pairs of alleles like in the case ofpurifying selection. Computer simulations have shown that switching in-betweencomplementation and purification strategies has a character of a phasetransition. This is also responsible for specific distribution of recombinationevents observed along eukaryotic chromosomes - higher recombination rate isobserved in subtelomeric regions than in central parts of chromosomes - forsympatric speciation and probably for non-monotonous relation betweenreproduction potential and genetic distance between parents.



Autor: Stanislaw Cebrat, Dietrich Stauffer, Wojciech Waga

Fuente: https://arxiv.org/







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