Vol 9: Interrelationships between ALOX5AP Polymorphisms, Serum Leukotriene B4 Level and Risk of Acute Coronary Syndrome.Reportar como inadecuado



 Vol 9: Interrelationships between ALOX5AP Polymorphisms, Serum Leukotriene B4 Level and Risk of Acute Coronary Syndrome.


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This article is from PLoS ONE, volume 9.AbstractBackground: We investigated the relationships between the ALOX5AP gene rs10507391 and rs4769874 polymorphisms, serum levels of leukotriene LT B4, and risk of acute coronary syndrome ACS. Methods: A total of 709 participants, comprising 508 ACS patients ACS group and 201 noncoronary artery disease patients with chest pain control group were recruited from the Han population of the Changwu region in China. Two polymorphic loci were genotyped using polymerase chain reaction and restriction fragment length polymorphism analysis. Serum LTB4 level was determined by enzyme-linked immunosorbent assay. Results: Serum LTB4 levels were significantly higher P



Autor: He, Guoping; Ye, Shan; Hui, Jingjiao; Shen, Dandan; Qi, Chuanping; Xu, Lianhong; Qian, Yichao

Fuente: https://archive.org/



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