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Kanakapura Basavaiah ; Kanakapura Basavaiah Vinay ; Hosakere Doddarevanna Revanasiddappa ;Journal of the Mexican Chemical Society 2010, 54 (4)

Autor: Nagaraju Rajendraprasad

Fuente: http://www.redalyc.org/


Introducción



Journal of the Mexican Chemical Society ISSN: 1870-249X editor.jmcs@gmail.com Sociedad Química de México México Rajendraprasad, Nagaraju; Basavaiah, Kanakapura; Basavaiah Vinay, Kanakapura; Revanasiddappa, Hosakere Doddarevanna Sensitive and Selective Extractive Spectrophotometric Method for the Determination of Hydroxyzine Dihydrochloride in Pharmaceuticals Journal of the Mexican Chemical Society, vol.
54, núm.
4, octubre-diciembre, 2010, pp.
233-239 Sociedad Química de México Distrito Federal, México Available in: http:--www.redalyc.org-articulo.oa?id=47521542009 How to cite Complete issue More information about this article Journals homepage in redalyc.org Scientific Information System Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Non-profit academic project, developed under the open access initiative J.
Mex.
Chem.
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2010, 54(4), 233-239 Sensitive in Pharmaceuticals 233 Article and Selective Extractive Spectrophotometric Method for the Determination of Hydroxyzine Dihydrochloride © 2010, Sociedad Química de México ISSN 1870-249X Sensitive and Selective Extractive Spectrophotometric Method for the Determination of Hydroxyzine Dihydrochloride in Pharmaceuticals Nagaraju Rajendraprasad, Kanakapura Basavaiah,* Kanakapura Basavaiah Vinay and Hosakere Doddarevanna Revanasiddappa Department of Studies in Chemistry, Manasagangothri, University of Mysore, Mysore 570 006, India.
e-mail: basavaiahk@ yahoo.co.in Received June 17, 2010; accepted September 10, 2010 Abstract.
Hydroxyzine dihydrochloride (HDH), a piperazine H1receptor antagonist and antihistamine, is a rapid acting anxiolytic used principally as an anti-emetic.
A sensitive, selective, and precise and accurate spectrophotometric method based on the formation of an ion-pair with orange II (ORG II) as ion-pair complexing agent was developed and validated for the determination of HDH in pharmaceuticals.
The chloroform-extractable ion-pair complex exhibited...





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