Vol 5: Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE-ADAM17.Reportar como inadecuado



 Vol 5: Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE-ADAM17.


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This article is from Cell Death & Disease, volume 5.AbstractTransforming growth factor-beta (TGF-β) plays a dual role in hepatocytes, inducing both pro- and anti-apoptotic responses, whose balance decides cell fate. Survival signals are mediated by the epidermal growth factor receptor (EGFR) pathway, which is activated by TGF-β in these cells. Ca

Autor: Moreno-Caceres, J; Caja, L; Mainez, J; Mayoral, R; Martin-Sanz, P; Moreno-Vicente, R; del Pozo, M A; Dooley, S; Egea, G; Fabregat, I

Fuente: https://archive.org/







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