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Journal of Medical Case Reports

, 3:11

First Online: 13 January 2009Received: 01 February 2008Accepted: 13 January 2009DOI: 10.1186-1752-1947-3-11

Cite this article as: Lakshminarayanan, V. & Ranganathan, K. J Med Case Reports 2009 3: 11. doi:10.1186-1752-1947-3-11


IntroductionOral melanoacanthoma is a rare, benign pigmented lesion characterized clinically by the sudden appearance and rapid growth of a macular brown-black lesion and histologically by acanthosis of the superficial epithelium and proliferation of dendritic melanocytes.

Case presentationWe present a case report of oral melanoacanthoma in a 24-year-old Asian Indian man. He presented with an intra-oral brown macular lesion on the left buccal mucosa with a duration of one and a half months. Microscopic examination revealed acanthosis of stratified squamous surface epithelium and dendritic melanocytes diffusely distributed in the epithelium; the Masson-Fontana silver impregnation technique was used to demonstrate the dendritic melanocytes. Based on the history, clinical features and histological presentation, the lesion was diagnosed as melanoacanthoma.

ConclusionThis is the first reported instance of oral melanoacanthoma in the Indian sub-continent. This report details the course of the lesion from diagnosis to its resolution. Melanoacanthoma must be differentiated from other intra-oral pigmented lesions and biopsy may be required to rule out melanoma.

Electronic supplementary materialThe online version of this article doi:10.1186-1752-1947-3-11 contains supplementary material, which is available to authorized users.

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Author: Vidya Lakshminarayanan - Kannan Ranganathan

Source: https://link.springer.com/

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