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Journal of Medical Case Reports

, 10:51

First Online: 08 March 2016Received: 26 August 2015Accepted: 30 January 2016DOI: 10.1186-s13256-016-0821-y

Cite this article as: Barbarash, L., Rutkovskaya, N., Barbarash, O. et al. J Med Case Reports 2016 10: 51. doi:10.1186-s13256-016-0821-y


BackgroundThe problem of prosthetic heart valve selection in fertile women with acquired heart defects remains crucial in modern cardiology. Mechanical heart valves require lifelong indirect anticoagulant therapy, which has significant fetal toxicity and is unacceptable for women planning pregnancy. Bioprosthetic heart valves are the best choice for fertile women; however, their durability is limited, and reoperations are required.

Case presentationWe describe the clinical case of a 21-year-old Russian woman with infectious endocarditis who underwent heart valve replacement with an epoxy-treated mitral valve prosthesis.

ConclusionsEpoxy-treated bioprosthetic heart valves can be used without long-term anticoagulant therapy because of their optimal hemodynamic functional parameters. Moreover, their high thromboresistance and resistance to infection improve patients’ quality of life in their late postoperative period. We recommend these valves both in older persons and in young patients including women who are planning pregnancy.

KeywordsBioprosthesis Childbirth Fertile women Pregnancy AbbreviationsAHAAmerican Heart Association

AHDAcquired heart disease


ESCEuropean Society of Cardiology

NYHANew York Heart Association

UFHUnfractionated heparin therapy

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Autor: Leonid Barbarash - Natalya Rutkovskaya - Olga Barbarash - Yuri Odarenko - Alexander Stasev - Evgenya Uchasova


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