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BMC Public Health

, 16:234

Chronic Disease epidemiology

Abstract

BackgroundThere is a paucity of data on the distribution of disease severity. In this study, we estimated disease severity distributions in South Korea using two EQ-5D-3L population surveys.

MethodsA total of 110 health states for 35 diseases with 2–5 severity levels e.g., mild, moderate, severe were included in this study. A general population of 360 participants from the areas surrounding Seoul and Gyunggi evaluated these health states using EQ-5D-3L via face-to-face interviews and a paper questionnaire. The EQ-5D indices were used to measure the severity levels of health states and used as the cutoff points for the disease severity distributions. Finally, these cutoff points were applied to disease prevalence data with EQ-5D-3L, which were obtained from the Korean National Health and Nutrition Examination Surveys KNHNES and Korean Community Health Survey, in order to estimate the disease severity distributions.

ResultsThe severity distributions of 8 diseases were estimated, including asthma, angina, stroke, chronic obstructive pulmonary disease, major depressive disorder, musculoskeletal problems in the legs, anemia, and allergic rhinitis and conjunctivitis. For example, the EQ-5D indices for chronic obstructive pulmonary disease severity were 0.929, 0.742, and 0.620, and the cut-off points were 0.835 between mild and moderate and 0.681 between moderate and severe. Using these cutoff points, the distributions of chronic obstructive pulmonary disease severity were 66.5 % mild, 23.3 % moderate, and 10.1 % severe according to KNHNES.

ConclusionsThe estimated severity distributions in this study can be used as a valid calculation of the disease burden in the general population.

KeywordsDisease severity Prevalence EQ-5D AbbreviationsCOPDchronic obstructive pulmonary disease

DALYsdisability adjusted life years

GBDglobal burden of disease

HRQoLhealth related quality of life

KCHSKorean Community Health Survey

KNHNESKorean National Health and Nutrition Examination Surveys

YLDsyears lived with disability

YLLsyears of life lost

Electronic supplementary materialThe online version of this article doi:10.1186-s12889-016-2904-5 contains supplementary material, which is available to authorized users.

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Autor: Minsu Ock - Min-Woo Jo - Young-hoon Gong - Hyeon-Jeong Lee - Jiho Lee - Chang Sun Sim

Fuente: https://link.springer.com/







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