Invasive urothelial carcinoma, lymphoma-like-plasmacytoid variant, successfully treated by radical cystectomy with adjuvant chemotherapy: a case reportReportar como inadecuado




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Journal of Medical Case Reports

, 10:48

First Online: 08 March 2016Received: 25 October 2015Accepted: 06 January 2016DOI: 10.1186-s13256-016-0806-x

Cite this article as: Ohtaka, M., Kawahara, T., Kumano, Y. et al. J Med Case Reports 2016 10: 48. doi:10.1186-s13256-016-0806-x

Abstract

BackgroundInvasive urothelial carcinoma, lymphoma-like-plasmacytoid variant, is a rare histological type of bladder cancer similar to plasma cells and is an aggressive variant of urothelial carcinoma associated with a poor prognosis.

Case presentationA 41-year-old Asian man was referred to our hospital due to macroscopic hematuria. Cystoscopy detected a non-papillary tumor, and a transurethral resection of the bladder tumor revealed pT1N0M0 bladder cancer. A pathological examination showed high-grade invasive urothelial carcinoma and a component of signet ring cell carcinoma. A follow-up of the transurethral resection with radical cystectomy was carried out, and a pathological examination showed infiltrating urothelial carcinoma, with partial features of the plasmacytoid variant. We added chemotherapy treatment with gemcitabine and cisplatin for two cycles. Our patient has been free from recurrence for 2 years.

ConclusionsWe herein report the case of a patient with a plasmacytoid variant of urothelial carcinoma controlled with radial cystectomy and subsequent chemotherapy.

KeywordsUrothelial carcinoma Plasmacytoid variant Gemcitabine Cisplatin Radical cystectomy AbbreviationsCTComputed tomography

GCGemcitabine and cisplatin

HPFhigh-power field

MRIMagnetic resonance imaging

M-VACMethotrexate, vinblastine, doxorubicin and cisplatin

PUCInvasive urothelial carcinoma, lymphoma-like-plasmacytoid variant

TUR-BtTransurethral resection of a bladder tumor

UCUrothelial carcinoma

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Autor: Mari Ohtaka - Takashi Kawahara - Yohei Kumano - Yoko Maeda - Takuya Kondo - Taku Mochizuki - Hiroaki Ishida - Yusuke Hatto

Fuente: https://link.springer.com/







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