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BMC Medicine

, 12:192

First Online: 31 October 2014Received: 23 July 2014Accepted: 26 September 2014DOI: 10.1186-s12916-014-0192-4

Cite this article as: Bunn, F., Burn, AM., Goodman, C. et al. BMC Med 2014 12: 192. doi:10.1186-s12916-014-0192-4


BackgroundEvidence suggests that amongst people with dementia there is a high prevalence of comorbid medical conditions and related complaints. The presence of dementia may complicate clinical care for other conditions and undermine a patient’s ability to manage a chronic condition. The aim of this study was to scope the extent, range and nature of research activity around dementia and comorbidity.

MethodsWe undertook a scoping review including all types of research relating to the prevalence of comorbidities in people with dementia; current systems, structures and other issues relating to service organisation and delivery; patient and carer experiences; and the experiences and attitudes of service providers. We searched AMED, Cochrane Library, CINAHL, PubMed, NHS Evidence, Scopus, Google Scholar searched 2012, Pubmed updated 2013, checked reference lists and performed citation searches on PubMed and Google Scholar ongoing to February 2014.

ResultsWe included 54 primary studies, eight reviews and three guidelines. Much of the available literature relates to the prevalence of comorbidities in people with dementia or issues around quality of care. Less is known about service organisation and delivery or the views and experiences of people with dementia and their family carers. There is some evidence that people with dementia did not have the same access to treatment and monitoring for conditions such as visual impairment and diabetes as those with similar comorbidities but without dementia.

ConclusionsThe prevalence of comorbid conditions in people with dementia is high. Whilst current evidence suggests that people with dementia may have poorer access to services the reasons for this are not clear. There is a need for more research looking at the ways in which having dementia impacts on clinical care for other conditions and how the process of care and different services are adapting to the needs of people with dementia and comorbidity. People with dementia should be included in the debate about the management of comorbidities in older populations and there needs to be greater consideration given to including them in studies that focus on age-related healthcare issues.

KeywordsDementia Comorbidity Diabetes Stroke Visual impairment Scoping review AbbreviationsAMDage-related macular degeneration

AMEDAllied and Complementary Medicine Database

CENTRALCochrane Central Register of Controlled Trials

CDSRCochrane Database of Systematic Reviews

CIcognitive impairment

DAREDatabase of

Abstracts of Reviews of Effectiveness

HTAhealth technology assessment

MCImild cognitive impairment

RCTrandomised controlled trial

VIvisual impairment

Electronic supplementary materialThe online version of this article doi:10.1186-s12916-014-0192-4 contains supplementary material, which is available to authorized users.

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Autor: Frances Bunn - Anne-Marie Burn - Claire Goodman - Greta Rait - Sam Norton - Louise Robinson - Johan Schoeman - Carol Brayn


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