Evaluation of the left and right ventricular systolic and diastolic function in asthmatic childrenReport as inadecuate

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BMC Cardiovascular Disorders

, 16:145

Non-coronary artery cardiac disease


BackgroundAsthma is the most common cause of respiratory disorders among children. We aimed to investigate left LV and right RV ventricular function in asthmatic children as detected by conventional and tissue Doppler echocardiography.

MethodsFifty pediatric patients with asthma and forty healthy children were studied. Pulmonary function tests, electrocardiography and echocardiographic examinations were performed on all children.

ResultsRate-corrected velocity of circumferential fiber shortening VCFc p = 0.044, the ratio between heights of early and late diastolic flow velocity peaks E-A p = 0.019 and LV end-systolic wall stress ESWSm was lower p = 0.003, RV stroke volume SV p = 0.002, LV SV p = 0.001, tricuspid annular plane systolic excursion TAPSE p = 0.034, tricuspid annular peak velocity during systole S’ p = 0.022, tricuspid and mitral early diastolic velocities E’ p = 0.012, p = 0.003 respectively were lower in asthmatic children than controls. The mitral valve ejection time ET was high in asthmatic group p = 0.027.

FEV1 was positively correlated with isovolumetric relaxation time IVRT p = 0.018 r = 0.382 and mitral ET p = 0.018 r = 0.381. PEF was negatively correlated with the RV work index p = 0.032 r = -0.348 and LV work index p = 0.005 r = -0.457.

ConclusionAlthough cardiac systolic function was found to be impaired in asthmatic patients, contrary to the literature, diastolic dysfunction was not observed in these patients, even by tissue Doppler imaging, and this finding may be attributed to using inhaled corticosteroid

KeywordsAsthma Children Echocardiography Tissue Doppler imaging Ventricular function  Download fulltext PDF

Author: Esra Akyüz Özkan - Hashem E. Khosroshahi

Source: https://link.springer.com/

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