Short-term effects of intragastric balloon in association with conservative therapy on weight loss: a meta-analysisReportar como inadecuado

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Journal of Translational Medicine

, 13:246

Nutrition and metabolism


Obesity is an epidemic chronic disease which is a risk factor for a number of serious medical conditions. Intragastric balloon, as an alternative, non-surgical treatment approach for the management of obesity, was rejected in previous evidence-based reviews. The object of this review is updating the data and confirming the safety and efficacy of the procedure. In this review, systematic literature retrieve of MEDLINE, EMBASE, CENTRAL and other information sources was performed from inception to December 2014. The quality of selected studies was assessed and meta-analyses of weighted mean differences were made using the inverse variance method. Meta-analyses presented significant effect sizes of −8.9 kg, −3.1 kg-m and −21.0% for SMG as well as of −1.5 kg and −1.2 kg-m for LSG, favoring the intervention group. Safety analysis showed that minor complications occurred at a high rate in intervention group, however, no serious or fatal complication was reported in these studies. In conclusion, the current review presents that short-term efficacy for 6 months treatment of intragastric balloon in association with conservative therapy is clinically significant.

KeywordsObesity Intragastric balloon Meta-analysis Efficacy Safety AbbreviationsIGBintragastric balloon

WLweight loss

EWLexcess weight loss

WMDweighted mean difference

CIconfidence interval

LSGless than six months group

SMGsix months group

PRISMAPreferred Reporting Items for Systematic Reviews and Meta-Analyses

Yiyuan Zheng and Miao Wang contributed equally to this work and should be considered co-first authors.

Electronic supplementary materialThe online version of this article doi:10.1186-s12967-015-0607-9 contains supplementary material, which is available to authorized users.

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Autor: Yiyuan Zheng - Miao Wang - Songhua He - Guang Ji


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