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Evidence-Based Complementary and Alternative MedicineVolume 2012 2012, Article ID 783923, 8 pages

Review Article

Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China

Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China

Received 13 January 2012; Revised 30 May 2012; Accepted 4 June 2012

Academic Editor: Shi-Bing Su

Copyright © 2012 Zhen Chen and Peng Wang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In traditional Chinese medicine TCM clinical practice, ZHENG also known as syndrome helps to guide design of individualized treatment strategies. In this study, we investigated the clinical use of ZHENG in TCM-treated cancer patients by systematically analyzing data from all relevant reports in the Chinese-language scientific literature. We aimed to determine the clinical ZHENG distributions in six common cancers lung, liver, gastric, breast, colorectal, and pancreatic with the expectation of uncovering a theoretical basis for TCM ZHENG as a clinical cancer treatment. In addition, we also reviewed the molecular basis underlying Xue-Yu blood stasis, Shi-Re dampness-heat, Yin-Xu Yin deficiency, and Pi-Xu spleen deficiency ZHENG that are commonly found in cancer patients. The results from our summary study provide insights into the potential utility of TCM ZHENG and may contribute to a better understanding of the molecular basis of TCM ZHENG in cancer.

Autor: Zhen Chen and Peng Wang



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