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BMC Cancer

, 16:801

Medical and radiation oncology

Abstract

BackgroundMost cases of disseminated carcinomatosis of the bone marrow DCBM arise from gastric cancer. DCBM from pancreatic cancer is very rare. We herein present a case of DCBM from pancreatic cancer.

Case presentationA 57-year-old man was referred to our hospital for severe lumbago. Laboratory data indicated that he suffered from disseminated intravascular coagulation DIC. Non-contrast abdominal computed tomography CT revealed multiple bone masses but no other abnormal findings. Left iliac bone marrow biopsy revealed poorly differentiated adenocarcinoma cells. Positron emission tomography PET-CT showed diffuse abnormal uptake in the bones and tail of the pancreas. Contrast whole-body CT showed a tumor measuring approximately 28 mm in diameter with poor enhancement in the tail of the pancreas. The patient’s final diagnosis was pancreatic cancer located in the tail of the pancreas with diffuse bone metastases and DIC. His DCBM was thus believed to originate from the pancreatic cancer. He succumbed to the disease approximately 2 months after admission to our hospital.

ConclusionWe herein describe a case of pancreatic cancer located in the tail of the pancreas with diffuse bone metastases and DIC, which, in our case, was DCBM. Therefore, in cases of DCBM with an unknown primary tumor, pancreatic cancer should be considered during differential diagnosis.

KeywordsDisseminated carcinomatosis of the bone marrow Disseminated intravascular coagulation Diffuse bone metastases Pancreatic cancer AbbreviationsCA 19-9Carbohydrate antigen 19-9

CEACarcinoembryonic antigen

CTComputed tomography

DCBMDisseminated carcinomatosis of the bone marrow

DICDisseminated intravascular coagulation

PAPProstatic acid phosphatase

PCUPalliative care unit

PETPositron emission tomography

TTF-1Thyroid transcription factor-1

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Autor: Hiroki Namikawa - Yasuhiko Takemoto - Ayako Makuuchi - Masanori Kobayashi - Shigeki Kinuhata - Mina Morimura - Takashi Ikeb

Fuente: https://link.springer.com/







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