Acupuncture for Frequent Migraine: A Randomized, Patient-Assessor Blinded, Controlled Trial with One-Year Follow-UpReportar como inadecuado

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Evidence-Based Complementary and Alternative Medicine - Volume 2015 2015, Article ID 920353, 14 pages -

Research Article

TCM Research Program, Health Innovations Research Institute HIRi, School of Health Sciences, RMIT University, Bundoora, VIC 3083, Australia

Department of Medicine, Royal Melbourne Hospital, Parkville, VIC 3052, Australia

School of Mathematical and Geospatial Science, RMIT University, Bundoora, VIC 3083, Australia

Received 17 December 2014; Accepted 23 March 2015

Academic Editor: Karen J. Sherman

Copyright © 2015 Yanyi Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. This study aimed to evaluate the efficacy and safety of manual acupuncture as a prophylaxis for frequent migraine. Methods. Fifty frequent migraineurs were randomly allocated to receive 16 sessions of either real acupuncture RA = 26 or sham acupuncture SA = 24 during 20 weeks. The primary outcomes were days with migraine over four weeks, duration, and intensity of migraine and the number of responders with more than 50% reduction of migraine days. The secondary outcomes were the relief medication, quality of migraine, quality of life, and pressure pain thresholds. Results. The two groups were comparable at baseline. At the end of the treatment, when compared with the SA group, the RA group reported significant less migraine days RA: 5.2 ± 5.0; SA: 10.1 ± 7.1; , less severe migraine RA: 2.18 ± 1.05; SA: 2.93 ± 0.61; , more responders RA: 19 versus SA: 7, and increased pressure pain thresholds. No other group difference was found. Group differences were maintained at the end of the three-month follow-up, but not at the one-year follow-up. No severe adverse event was reported. Blinding was successful. Discussion. Manual acupuncture was an effective and safe treatment for short-term relief of frequent migraine in adults. Larger trials are warranted.

Autor: Yanyi Wang, Charlie Changli Xue, Robert Helme, Cliff Da Costa, and Zhen Zheng



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