Combining short stent implantation and drug-eluting stenting for routine use yields a low restenosis rateReport as inadecuate




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Current Controlled Trials in Cardiovascular Medicine

, 6:18

First Online: 13 December 2005Received: 21 September 2005Accepted: 13 December 2005DOI: 10.1186-1468-6708-6-18

Cite this article as: Dietz, U., Dauer, C. & Lambertz, H. Trials 2005 6: 18. doi:10.1186-1468-6708-6-18

Abstract

BackgroundStent length serves as a predictor of restenosis in use of bare metal stents BMS. This has been demonstrated in a feasibility study that used a single short BMS implant <9 mm in a high proportion of lesions; the study observed a low rate of restenosis.

MethodsWe performed a pilot prospective study to investigate in a series of consecutive patients the immediate and long-term effects of implantation of either 1 a single short BMS for all lesions with low probability of restenosis or 2 a drug-eluting stent DES for all other lesions.

ResultsThe 200 patients studied had 236 coronary artery lesions that were treated with short BMS in 168-236 patients 71.2% and with DES in 68-236 patients 28.8%. Angiographic success was achieved in 230-236 lesions 97.5% and procedural success in 194-200 patients 97.0%. Restenosis occurred in 15-153 lesions 9.8% after short BMS, in 3-62 lesions 4.8% after DES, and in 18-215 of all lesions 8.4% angiographically controlled after six to eight months. Target vessel revascularization was performed in 16-218 lesion 7.4%.

ConclusionMost of the coronary artery lesions in this small group of consecutive patients were treated sufficiently with a single BMS implant. This differential approach of treating suitable lesions in medium- to large-sized vessels with a single short BMS device and treating all other lesions with a DES implant resulted in a low incidence of restenosis.

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Author: Ulrich Dietz - Cheryl Dauer - Heinz Lambertz

Source: https://link.springer.com/







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