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Journal of OsteoporosisVolume 2011 2011, Article ID 457591, 6 pages

Research Article

Department of Physical Medicine and Rehabilitation, Mayo Clinic, College of Medicine, Rochester, MN 55905, USA

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, College of Medicine, Rochester, MN 55905, USA

Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, College of Medicine, Rochester, MN 55905, USA

Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, College of Medicine, Rochester, MN 55905, USA

Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Internal Medicine, Mayo Clinic, College of Medicine, Rochester, MN 55905, USA

Received 5 May 2011; Revised 29 July 2011; Accepted 8 August 2011

Academic Editor: Harri Sievänen

Copyright © 2011 Lisa-Ann Wuermser et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

To address the epidemiology of rib fractures, an age- and sex-stratified random sample of 699 Rochester, Minnesota, adults age 21–93 years was followed in a long-term prospective study. Bone mineral density BMD was assessed at baseline, and fractures were ascertained by periodic interview and medical record review. During 8560 person-years of followup median, 13.9 years, 56 subjects experienced 67 rib fracture episodes. Risk factors for falling predicted rib fractures as well as BMD, but both were strongly age-related. After age-adjustment, BMD was associated with rib fractures in women but not men. Importantly, rib fractures attributed to severe trauma were associated with BMD in older individuals of both sexes. Self-reported heavy alcohol use doubled fracture risk but did not achieve significance due to limited statistical power. Bone density, along with heavy alcohol use and other risk factors for falling, contributes to the risk of rib fractures, but no one factor predominates. Older women with rib fractures, regardless of cause, should be considered for an osteoporosis evaluation, and strategies to prevent falling should be considered in both sexes.





Author: Lisa-Ann Wuermser, Sara J. Achenbach, Shreyasee Amin, Sundeep Khosla, and L. Joseph Melton III

Source: https://www.hindawi.com/



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