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Case Reports in Ophthalmological MedicineVolume 2012 2012, Article ID 413010, 3 pages

Case ReportDepartment of Ophthalmology, Campus Bio-Medico University of Rome, Via Alvaro del Portillo 21, 00128 Rome, Italy

Received 4 November 2011; Accepted 16 January 2012

Academic Editors: C.-Y. Cheng, T. Hayashi, and E. B. Rodrigues

Copyright © 2012 Flavio Mantelli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We report the case of a patient diagnosed with Avellino corneal dystrophy ACD who developed diffuse interstitial keratitis following excimer laser insitu keratomileusis LASIK. ACD is an autosomal dominant corneal dystrophy characterized by multiple asymmetric stromal opacities that impair vision. Accepted treatments for this condition include corneal transplantation and phototherapeutic keratectomy PTK. Our patient underwent LASIK at another institution to correct myopia. LASIK and photorefractive keratectomy PRK are usually contraindicated in ACD for the high risk of disease recurrence and postoperative complications. The patient came to our attention lamenting blurry vision, decreased visual acuity, and photophobia. Ophthalmologic examination revealed bilateral interstitial keratitis, also known as “sands of Sahara”, a seldom-seen complication of LASIK characterized by fine and diffuse granular infiltrates at the surgical flap interface.The risk of developing interstitial keratitis, as in the case presented here, represents another valid reason for avoiding LASIK in patients with ACD.

Autor: Flavio Mantelli, Alessandro Lambiase, Antonio Di Zazzo, and Stefano Bonini



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