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BMC Proceedings

, 11:1

First Online: 27 January 2017DOI: 10.1186-s12919-016-0069-y

Cite this article as: Saadatian-Elahi, M., Bloom, D., Plotkin, S. et al. BMC Proc 2017 11Suppl 2: 1. doi:10.1186-s12919-016-0069-y


BackgroundVaccination is a complex ecosystem with several components that interact with one another and with the environment. Today’s vaccine ecosystem is defined by the pursuit of polio eradication, the drive to get as many of the new vaccines to as many people as possible and the research and development against immunologically challenging diseases. Despite these successes, vaccine ecosystem is facing keys issues with regard to supply-distribution and cost-profitability asymmetry that risk slowing its global growth.

The conference -Vaccination ecosystem health check: achieving impact today and sustainability for tomorrow- held in Annecy-France January 19–21, 2015 took stock of the health of today’s vaccination ecosystem and its ability to reliably and sustainably supply high-quality vaccines while investing in tomorrow’s needed innovation.

Main findingsSmall and decreasing numbers of suppliers-manufacturing facilities; paucity of research-driven companies; regulatory pressures; market uncertainties; political prioritization; anti-vaccine movements-complacency; and technological and programmatic issues were acknowledged as the major challenges that could weaken today’s vaccination ecosystem. The expert panel discussed also drivers and barriers to a sustainable vaccination ecosystem; the metrics of a vaccination ecosystem; and what should be added, removed, increased, or reduced to maintain the health of the vaccination ecosystem.

KeywordsConference report Vaccination ecosystem Vaccine demand and supply Vaccine research and development Electronic supplementary materialThe online version of this article doi:10.1186-s12919-016-0069-y contains supplementary material, which is available to authorized users.

Autor: Mitra Saadatian-Elahi - David Bloom - Stanley Plotkin - Valentina Picot - Jacques Louis - Michael Watson


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