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Genome Medicine

, 9:10

First Online: 27 January 2017DOI: 10.1186-s13073-017-0402-8

Cite this article as: Finotello, F. & Trajanoski, Z. Genome Med 2017 9: 10. doi:10.1186-s13073-017-0402-8

Abstract

The immunosuppressive action of regulatory T Treg cells is one mechanism attributed to the limited success of cancer immunotherapies with checkpoint blockers. Two recent studies report distinct transcriptional profiles of tumor-infiltrating Treg cells and expression of specific molecules, suggesting novel strategies to overcome resistance to cancer immunotherapy.

AbbreviationsCRCColorectal cancer

NSCLCNon-small-cell lung cancer

TNBCTriple-negative breast cancer

Treg cellRegulatory T cell





Autor: Francesca Finotello - Zlatko Trajanoski

Fuente: https://link.springer.com/







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