The association between secondhand smoke and the risk of developing acute coronary syndromes, among non-smokers, under the presence of several cardiovascular risk factors: The CARDIO2000 case-control studyReportar como inadecuado




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BMC Public Health

, 2:9

First Online: 24 May 2002Received: 11 November 2001Accepted: 24 May 2002DOI: 10.1186-1471-2458-2-9

Cite this article as: Panagiotakos, D.B., Chrysohoou, C., Pitsavos, C. et al. BMC Public Health 2002 2: 9. doi:10.1186-1471-2458-2-9

Abstract

BackgroundThe purpose of this study was to investigate the association between secondhand smoke and the risk of developing a first event of acute coronary syndromes ACS, i.e. acute myocardial infarction or unstable angina, among non-smokers, in relation to the presence of several other cardiovascular risk factors.

MethodsEight hundred and forty-eight patients with first event of ACS and 1078 cardiovascular disease-free matched controls completed a detailed questionnaire regarding their exposure to secondhand smoke, among other investigated parameters.

ResultsTwo hundred and ninety–seven 35% of the patients and 259 24% of the controls were defined as secondhand smokers. After controlling for several potential confounders, the results showed that non-smokers occasionally < 3 time per week exposed to cigarette smoke were associated with 26% higher risk of ACS OR = 1.26, P-value < 0.01 compared to non-smokers not exposed to smoke, while regular exposure is associated with 99% higher risk of developing ACS OR = 1.99, P-value < 0.001. Moreover, the previous risk increases progressively from 15% to 256% if one or more of the classical cardiovascular risk factors i.e. hypertension, hypercholesterolemia, diabetes mellitus, sedentary life and family history of premature coronary heart disease are present.

ConclusionsConsequently, this study supports the hypothesis that even occasional secondhand smoke increases the risk of developing acute coronary syndromes, especially when other risk factors are present. Given the high prevalence of cigarette smoking, the public health consequences of passive smoking with regard to coronary heart disease are important.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-2458-2-9 contains supplementary material, which is available to authorized users.





Autor: Demosthenes B Panagiotakos - Christina Chrysohoou - Christos Pitsavos - Ioanna Papaioannou - John Skoumas - Christodoulos S

Fuente: https://link.springer.com/







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