Short-Term Efficacy of Pudilan Keyanning Toothpaste in Treatment of Minor Recurrent Aphthous UlcersReportar como inadecuado

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Evidence-Based Complementary and Alternative Medicine - Volume 2016 2016, Article ID 9125327, 7 pages -

Research Article

Department of Preventive Dentistry, West China School and Hospital of Stomatology, Sichuan University, Chengdu 610041, China

Nanjing University of Chinese Medicine, Nanjing 210023, China

Received 29 June 2016; Revised 18 September 2016; Accepted 12 October 2016

Academic Editor: Jenny M. Wilkinson

Copyright © 2016 Yingming Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aim. To examine the potential of Pudilan Keyanning toothpaste PKT to treat minor aphthous ulcers MiAU. Method. A double-blind clinical trial was conducted in which 80 volunteers were randomly assigned to the PKT group or the control group . The control group used a placebo toothpaste containing no Pudilan extract. At baseline, after 3 days, and after 6 days the following parameters were recorded for the target ulcers: healing rate, healing period, pain visual analogue scale, VAS, areas of the target ulcerated lesions, degree of exudation, and hyperemia. Results. At the end of the study, the healing rate in the PKT group was 80%, compared to 50% in the control group . At day 6, the VAS scores, ulcer area, degree of exudation, and hyperemia were significantly different between the two groups, with better performance observed in the PKT group . Conclusion. PKT toothpaste appears to promote effective healing of MiAU.

Autor: Yingming Yang, Tao Zhang, Zibo Dong, Yang Wu, Xiao Hong, and Tao Hu



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