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Advances in UrologyVolume 2009 2009, Article ID 782985, 5 pages

Clinical Study

Department of Urology, Hokkaido Prefectural Esashi Hospital, Japan

Department of Urology, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan

Department of Urology, Furuya Hospital, Kitami 090-0065, Japan

Received 1 June 2009; Accepted 25 August 2009

Academic Editor: Flavio Trigo Rocha

Copyright © 2009 Yoshinori Tanaka et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. In women who reported a weak urinary stream, the efficacy of treatment chosen according to the urodynamic findings on pressure-flow study was prospectively evaluated. Materials and Methods. Twelve female patients with maximum flow rates of 10 mL-sec or lower were analyzed in the present study. At baseline, all underwent pressure-flow study to determine the degree of bladder outlet obstruction BOO and status of detrusor contractility on Schäfer's diagram. Distigmine bromide, 10 mg-d, was given to the patients with detrusor underactivity DUA defined as weak-very weak contractility, whereas urethral dilatation was performed using a metal sound for those with BOO linear passive urethral resistance relation 2–6. Treatment efficacy was evaluated using the International Prostate Symptom Score IPSS, uroflowmetry, and measurement of postvoid residual urine volume. Some patients underwent pressure-flow study after treatment. Results. Urethral dilatation was performed for six patients with BOO, while distigmine bromide was given to the remaining six showing DUA without BOO. IPSS, QOL index, and the urinary flow rate were significantly improved in both groups after treatment. All four of the patients with BOO and one of the three with DUA but no BOO who underwent pressure-flow study after treatment showed decreased degrees of BOO and increased detrusor contractility, respectively. Conclusions. Both BOO and DUA cause a decreased urinary flow rate in women. In the short-term, urethral dilatation and distigmine bromide are efficacious for female patients with BOO and those with DUA, respectively.

Autor: Yoshinori Tanaka, Naoya Masumori, Taiji Tsukamoto, Seiji Furuya, Ryoji Furuya, and Hiroshi Ogura



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