Coronary Spasm in Neurosurgical Patients and Role of Trigeminocardiac ReflexReportar como inadecuado

Coronary Spasm in Neurosurgical Patients and Role of Trigeminocardiac Reflex - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Neurology Research International - Volume 2014 2014, Article ID 974930, 5 pages -

Review Article

Department of Anesthesia and Perioperative Medicine, Health Sciences Center, University of Manitoba, 671 William Avenue, Winnipeg, Canada R3E 0Z2

University Hospital of Basel, Switzerland

Department of Research, University of Southampton, University Road, Southampton S017 1 BJ, UK

Received 19 October 2013; Accepted 8 December 2013; Published 27 January 2014

Academic Editor: Dirk Deleu

Copyright © 2014 Tumul Chowdhury et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Coronary artery spasm CAS is a rarely reported complication in neurosurgical patients and its main causative mechanism was attributed to vagal mediated responses. However, these may be the unusual manifestations of trigeminal cardiac reflex TCR which is a well established brain stem reflex observed in various neurosurgical patients. Methods and Results. In this review, we have searched for the case reports-papers related to intraoperative coronary spasm in neurosurgical patients and described the role of TCR in this regard. TCR is a possible mechanism in producing CAS in most of the cases in which stimulation occurred at or near the vicinity of trigeminal nerve. It is likely that TCR mediated coronary spasm may be a physiological mechanism and not related to actual myocardial insult apparent by cardiac enzymes or echocardiography studies in most of the cases. Some common risk factors may also exist related to occurrence of CAS as well as TCR. Conclusions. In conclusion, neurosurgical procedures occurring at the vicinity of trigeminal nerve may produce CAS even in previously healthy patients and may produce catastrophic consequences. There is a need for future reports and experimental studies on the interaction of TCR and pathophysiological mechanisms related to CAS.

Autor: Tumul Chowdhury, Cyrill Meuwly, Nora Sandu, Ronald B. Cappellani, and Bernhard Schaller



Documentos relacionados