Outcomes following percutaneous coronary revascularization among South Asian and Chinese CanadiansReportar como inadecuado




Outcomes following percutaneous coronary revascularization among South Asian and Chinese Canadians - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

BMC Cardiovascular Disorders

, 17:101

Coronary artery disease

Abstract

BackgroundPrevious data suggest significant ethnic differences in outcomes following percutaneous coronary revascularization PCI, though previous studies have focused on subgroups of PCI patients or used administrative data only. We sought to compare outcomes in a population-based cohort of men and women of South Asian SA, Chinese and -Other- ethnicity.

MethodsUsing a population-based registry, we identified 41,792 patients who underwent first revascularization via PCI in British Columbia, Canada, between 2001 and 2010. We defined three ethnic groups SA, 3904 9.3%; Chinese, 1345 3.2%; and all -Others- 36,543 87.4%. Differences in mortality, repeat revascularization RRV and target vessel revascularization TVR, at 30 days and from 31 days to 2 years were examined.

ResultsAdjusted mortality from 31 days to 2 years was lower in Chinese patients than in -Others- hazard ratio HR 0.72; 95% confidence interval CI 0.53-0.97, but not different between SAs and -Others-. SA patients had higher RRV at 30 days adjusted odds ratio OR 1.30; 95% CI: 1.12-1.51 and from 31 days to 2 years adjusted hazard ratio HR 1.17; 95% CI: 1.06-1.30 compared to -Others-. In contrast, Chinese patients had a lower rate of RRV from 31 days to 2 years adjusted HR 0.79; 95% CI: 0.64-0.96 versus -Others-. SA patients also had higher rates of TVR at 30 days adjusted OR 1.35; 95% CI: 1.10-1.66 and from 31 days to 2 years adjusted HR 1.19; 95% CI: 1.06-1.34 compared to -Others-. Chinese patients had a lower rate of TVR from 31 days to 2 years adjusted HR 0.76; 95% CI: 0.60-0.96.

ConclusionsSA had higher RRV and TVR rates while Chinese Canadians had lower rates of long-term RRV, compared to those of -Other- ethnicity. Further research to elucidate the reasons for these differences could inform targeted strategies to improve outcomes.

KeywordsCoronary artery disease Percutaneous coronary intervention Ethnicity Outcomes AbbreviationsBMIbody mass index

CABGcoronary artery bypass graft

CADcoronary artery disease

CIconfidence interval

HRhazard ratio

MImyocardial infarction

ORodds ratio

PCIpercutaneous coronary intervention

RRVrepeat revascularization

SASouth Asian

TVRtarget vessel revascularization





Autor: Martha H. Mackay - Robinder Singh - Robert H. Boone - Julie E. Park - Karin H. Humphries

Fuente: https://link.springer.com/







Documentos relacionados