Rationale and methods of the iFightDepression study: A double-blind, randomized controlled trial evaluating the efficacy of an internet-based self-management tool for moderate to mild depressionReportar como inadecuado




Rationale and methods of the iFightDepression study: A double-blind, randomized controlled trial evaluating the efficacy of an internet-based self-management tool for moderate to mild depression - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

BMC Psychiatry

, 17:143

Mood disorders

Abstract

BackgroundDuring the last decade online interventions have emerged as a promising approach for patients with mild-moderate depressive symptoms, reaching at large populations and representing cost-effective alternatives. The main objective of this double-blind, randomized controlled trial is to examine the efficacy of an internet-based self-management tool iFightDepression for mild to moderate depression as an add-on to treatment as usual TAU versus internet-based psychoeducation plus TAU.

MethodsA total of 310 participants with major depression disorder MDD will be recruited at four different mental-health facilities in Spain. Participants will be randomly allocated to one of two study arms: iFightDepression iFD tool + TAU vs. internet-based psychoeducation + TAU. Both interventions last for 8 weeks and there is a 12 weeks follow up. The primary outcome measure is changes in depressive symptoms assessed with the Hamilton Depression Rating Scale. Additionally, pre-post interventions assessments will include socio-demographic data, a brief medical and clinical history and self-reported measures of depressive symptoms, quality of life, functional impairments and satisfaction with the iFD tool.

DiscussioniFightDepression is an easy-prescribed tool that could increase the efficacy of conventional treatment and potentially reach untreated patients, shortening waiting lists to receive psychological treatment. Confirming the efficacy of the iFD internet-based self-management tool as an add-on treatment for individuals with mild to moderate depression will be clinically-relevant.

Trial registrationRegistration number NCT02312583. Clinicaltrials.gov. December 4, 2014.

KeywordsDepression Cognitive behavioural therapy Internet-based Self-management Primary care Randomized controlled trial AbbreviationsCBTCognitive behavioural therapy

CGI – IClinical global impression - improvement

CGI-SClinical global impression - severity

EAADEuropean alliance against depression

e-CRFElectronic clinical report form

FASTFunctioning assessment short test

HDRSHamilton depression rating scale

iFDiFightDepression

ITTIntention to treat

MDDMajor depressive disorder

MINIMini-international neuropsychiatric interview

PHQ-9Patient health questionnaire

PISPatient information sheet

PREDI-NUPreventing Depression and Improving Awareness through Networking in the European Union PREDI-NU

RDQRemission from depression questionnaire

TAUTreatment as usual

WHOWorld Health Organization





Autor: Azucena Justicia - Matilde Elices - Ana Isabel Cebria - Diego J. Palao - Jesús Gorosabel - Dolors Puigdemont - Javier de

Fuente: https://link.springer.com/







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