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BMC Musculoskeletal Disorders

, 18:183

Clinical rheumatology and osteoporosis


BackgroundThe primary purpose of this study is to assess the existing evidence on the cost-effectiveness of surgical interventions for the management of knee and hip osteoarthritis by systematically reviewing published economic evaluation studies.

MethodsA systematic review was conducted for the period 2004 to 2016. Electronic databases were searched to identify both trial and model based economic evaluation studies that evaluated surgical interventions for knee and hip osteoarthritis.

ResultsA total of 23 studies met the inclusion criteria and an assessment of these studies showed that total knee arthroplasty TKA, and total hip arthroplasty THA showed evidence of cost-effectiveness and improvement in quality of life of the patients when compared to non-operative and non-surgical procedures. On the other hand, even though delaying TKA and THA may lead to some cost savings in the short-run, the results from the study showed that this was not a cost-effective option.

ConclusionsTKA and THA are cost-effective and should be recommended for the management of patients with end stage-severe knee and hip OA. However, there needs to be additional studies to assess the cost-effectiveness of other surgical interventions in order for definite conclusions to be reached.

KeywordsOsteoarthritis Cost-effectiveness Costs Review AbbreviationsCHEERSConsolidated health economic evaluating reporting standard

DESDiscrete event simulation

EQ-5DEuroQoL five dimension

HAQHealth assessment questionnaire

HR-QoLHealth related quality of life

HTOHigh tibial osteotomy

HUIHealth utility index

ICERIncremental cost-effectiveness ratio

MoM-HRAMetal on metal hip resurfacing arthroplasty


QALYQuality adjusted life years

QHESQuality of health economics studies

SF-36Short form 36

SF-6DShort form 6D

THATotal hip arthroplasty

TKATotal knee arthroplasty

UKAUnicondylar knee arthroplasty

Electronic supplementary materialThe online version of this article doi:10.1186-s12891-017-1540-2 contains supplementary material, which is available to authorized users.

Autor: Hanin Kamaruzaman - Philip Kinghorn - Raymond Oppong


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