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Advances in HematologyVolume 2011 2011, Article ID 725219, 10 pages

Research ArticleWinship Cancer Institute, Emory University, 1365 Clifton Road, N.E. Building B, Suite 4302, Atlanta, GA 30322, USA

Received 2 July 2010; Accepted 19 October 2010

Academic Editor: Emili Montserrat

Copyright © 2011 Pareen Shenoy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Hodgkin lymphoma HL demonstrates heterogenous histologic findings, clinical presentation, and outcomes. Using the United States Surveillance, Epidemiology, and End Results SEER data we examined relationships between patient characteristics, clinical features at diagnosis, and survival in HL patients. From 2000 to 2007, 16,710 cases were recorded in 17 SEER registries. Blacks and Asians had low incidence black-white incidence rate ratio IRR 0.86, ; Asian-white IRR 0.43, . The bimodal pattern of incidence was less prominent for black males. Asians and Blacks presented at a mean age of 38 years compared to 42 years for Whites . Race was a predictor for survival with HR of 1.19 95% CI 1.11–1.28 for Blacks. Age was the most important predictor of survival HR for patients ≥45 years 5.08, 95% CI 4.86–5.31. These current patterns for presentation and outcomes of HL help to delineate key populations in order to explore risk factors for HL and strategies to improve treatment outcomes.





Autor: Pareen Shenoy, Alison Maggioncalda, Neha Malik, and Christopher R. Flowers

Fuente: https://www.hindawi.com/



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