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Abstract: This paper presents the fabrication process, characterization results andbasic functionality of silicon microneedles array with biodegradable tips. Inorder to avoid the main problems related to silicon microneedles : broking ofthe top part of the needles inside the skin, a simple solution can befabrication of microneedles array with biodegradable tips. The siliconmicroneedles array was fabricated by using reactive ion etching while thebiodegradable tips were performed using and anodization process that generatesselectively porous silicon only on the top part of the skin. The paper presentsalso the results of in vitro release of calcein using microneedles array withbiodegradable tips



Autor: B. Chen, J. Wei, Francis Tay, Y.T. Wong, C. Iliescu

Fuente: https://arxiv.org/







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