From the epidemiology of hepatitis E virus HEV within the swine reservoir to public health risk mitigation strategies: a comprehensive reviewReportar como inadecuado




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Veterinary Research

, 48:31

First Online: 25 May 2017Received: 06 March 2017Accepted: 19 April 2017DOI: 10.1186-s13567-017-0436-3

Cite this article as: Salines, M., Andraud, M. & Rose, N. Vet Res 2017 48: 31. doi:10.1186-s13567-017-0436-3

Abstract

Hepatitis E virus HEV is the causative agent of hepatitis E in humans, an emerging zoonosis mainly transmitted via food in developed countries and for which domestic pigs are recognised as the main reservoir. It therefore appears important to understand the features and drivers of HEV infection dynamics on pig farms in order to implement HEV surveillance programmes and to assess and manage public health risks. The authors have reviewed the international scientific literature on the epidemiological characteristics of HEV in swine populations. Although prevalence estimates differed greatly from one study to another, all consistently reported high variability between farms, suggesting the existence of multifactorial conditions related to infection and within-farm transmission of the virus. Longitudinal studies and experimental trials have provided estimates of epidemiological parameters governing the transmission process e.g. age at infection, transmission parameters, shedding period duration or lag time before the onset of an immune response. Farming practices, passive immunity and co-infection with immunosuppressive agents were identified as the main factors influencing HEV infection dynamics, but further investigations are needed to clarify the different HEV infection patterns observed in pig herds as well as HEV transmission between farms. Relevant surveillance programmes and control measures from farm to fork also have to be fostered to reduce the prevalence of contaminated pork products entering the food chain.

Electronic supplementary materialThe online version of this article doi:10.1186-s13567-017-0436-3 contains supplementary material, which is available to authorized users.





Autor: Morgane Salines - Mathieu Andraud - Nicolas Rose

Fuente: https://link.springer.com/







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