Pediatric emergency department visits and ambient Air pollution in the US State of Georgia: a case-crossover studyReport as inadecuate

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Journal Title:

Environmental Health


Volume 15, Number 1


BioMed Central | 2016-11-25, Pages 1-8

Type of Work:

Article | Final Publisher PDF

Abstract: Background: Estimating the health effects of ambient air pollutant mixtures is necessary to understand the risk of real-life air pollution exposures.Methods: Pediatric Emergency Department ED visit records for asthma or wheeze n = 148,256, bronchitis n = 84,597, pneumonia n = 90,063, otitis media n = 422,268 and upper respiratory tract infection URI n = 744,942 were obtained from Georgia hospitals during 2002–2008. Spatially-contiguous daily concentrations of 11 ambient air pollutants were estimated from CMAQ model simulations that were fused with ground-based measurements. Using a case-crossover study design, odds ratios for 3-day moving average air pollutant concentrations were estimated using conditional logistic regression, matching on ZIP code, day-of-week, month, and year.Results: In multipollutant models, the association of highest magnitude observed for the asthma-wheeze outcome was with -oxidant gases- O3, NO2, and SO2; the joint effect estimate for an IQR increase of this mixture was OR: 1.068 95% CI: 1.040, 1.097. The group of -secondary pollutants- O3 and the PM2.5 components SO4 2−, NO3−, and NH4+ was strongly associated with bronchitis OR: 1.090, 95% CI: 1.050, 1.132, pneumonia OR: 1.085, 95% CI: 1.047, 1.125, and otitis media OR: 1.059, 95% CI: 1.042, 1.077. ED visits for URI were strongly associated with -oxidant gases,-secondary pollutants,- and the -criteria pollutants- O3, NO2, CO, SO2, and PM2.5.Conclusions: Short-term exposures to air pollution mixtures were associated with ED visits for several different pediatric respiratory diseases.

Subjects: Environmental Sciences - Health Sciences, Medicine and Surgery - Health Sciences, Public Health - Research Funding: IH grant K01ES019877 and EPA STAR grant RD834799.

Keywords: Science and Technology - Life Sciences and Biomedicine - Environmental Sciences - Public, Environmental and Occupational Health - Environmental Sciences and Ecology - Air pollution - Pediatric Emergency Department Visits - Multipollutant model - CMAQ - FINE PARTICULATE MATTER - SHORT-TERM ASSOCIATIONS - HOSPITAL ADMISSIONS - TIME-SERIES - MULTIPOLLUTANT EXPOSURE - MEASUREMENT ERROR - HEALTH - ASTHMA - POLLUTANTS - ATLANTA -

Author: Qingyang Xiao, Yang Liu, James A. Mulholland, Armistead G. Russell, Lyndsey Darrow, Paige Tolbert, Matthew J. Strickland,



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