Chinese Herbal Medicine Weijing Decoction Combined with Pharmacotherapy for the Treatment of Acute Exacerbations of Chronic Obstructive Pulmonary DiseaseReportar como inadecuado




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Evidence-Based Complementary and Alternative MedicineVolume 2014 2014, Article ID 257012, 12 pages

Review Article

Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China

The 2nd Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China

Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou 510120, China

Traditional and Complementary Medicine Research Program, Health Innovations Research Institute, School of Health Sciences, RMIT University, Bundoora, Melbourne, VIC 3083, Australia

Received 17 June 2014; Accepted 11 July 2014; Published 6 August 2014

Academic Editor: Aiping Lu

Copyright © 2014 Shaonan Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To evaluate the efficacy and safety of Weijing decoction combined with routine pharmacotherapy RP for the treatment of acute exacerbations of chronic obstructive pulmonary disease AECOPD. Methods. Randomized controlled trials RCT evaluating Weijing decoction for AECOPD were included. English, Chinese, and Japanese databases were searched from their respective inceptions to June 2013. The methodological quality was assessed according to the Cochrane Collaboration’s risk of bias tool. All data were analyzed and synthesized using RevMan 5.2 software. Results. Fifteen 15 studies involving 986 participants were included. Participants were diagnosed with COPD in the acute exacerbation stage. In addition, most of studies reported that they included participants with the Chinese medicine syndrome, phlegm-heat obstructing the Lung. Weijing decoction combined with RP improved lung function forced expiratory volume in one second; FEV1, arterial blood gases PaO2 and PaCO2, clinical effective rate, and reduced inflammatory biomarkers TNF-α and IL-8 when compared with RP alone. No severe adverse events were reported in these studies. Conclusions. Weijing decoction appeared to be beneficial for AECOPD and well-tolerated when taken concurrently with RP, such as antibiotics, bronchodilators oral and inhaled, and mucolytics.





Autor: Shaonan Liu, Johannah Shergis, Xiankun Chen, Xuhua Yu, Xinfeng Guo, Anthony Lin Zhang, Chuanjian Lu, and Charlie Changli Xu

Fuente: https://www.hindawi.com/



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