Resection of a Catecholamine-Elaborating Retroperitoneal Paraganglioma Invading the Inferior Vena CavaReportar como inadecuado

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Case Reports in Surgery - Volume 2014 2014, Article ID 837054, 4 pages -

Case Report

Department of Radiation Oncology, Indiana University SOM, 535 Barnhill Drive, RT-041, Indianapolis, IN 46202, USA

Department of Pathology, Tulane University SOM, 1430 Tulane Avenue, SL-79, New Orleans, LA 70112, USA

Department of Surgery, Tulane University SOM, 1430 Tulane Avenue, SL-22, New Orleans, LA 70112, USA

Received 9 October 2014; Accepted 11 December 2014; Published 28 December 2014

Academic Editor: Hajime Imura

Copyright © 2014 E. M. Mannina et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Paragangliomas are rare tumors originating outside of the adrenal medulla which can be associated with catecholamine secretion or mass effect, one of which typically leads to their discovery. The differences between these tumors and traditional intra-adrenal pheochromocytomas are a subject of recent investigations. Standard of care therapy is medical management and surgical resection of the tumor. When tumors are biochemically active, medical optimization of the autonomic nervous system is a critical component to a safe, definitive resection. Tumors arising in the retroperitoneum present technical challenges for the surgeon as they are often large and difficult to access, making an oncologic resection much more difficult. Lastly, these tumors are mostly benign and rarely invade adjacent structures—an operative finding not always predicted by preoperative imaging—which, if present, adds significant complexity and risk to the resection. A case illustrating these challenges in the management of a biochemically active retroperitoneal paraganglioma invading the inferior vena cava follows.

Autor: E. M. Mannina, Z. Xiong, R. Self, and E. Kandil



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