Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City AreaReportar como inadecuado

Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Canadian Journal of Infectious Diseases - Volume 3 1992, Issue 4, Pages 179-184

Original Article

Laboratoire de virologie. Département de microbiologie, Faculté de médecine, Université Laval, Sainte-Foy, Québec, Canada

Hôtel-Dieu de Quêbec, Québec, Québec, Canada

Received 22 November 1990; Accepted 10 July 1991

Copyright © 1992 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Seroprevalence of antibodies against human herpesvirus 6 was determined in a sample of 303 randomly selected individuals from the Quebec City area. The influence of different variables on antibody litres was also evaluated. Human herpesvirus 6 was grown in the HSB-2 cell line, and antibody litres were measured by indirect immunofluorescence. Serum samples were collected from 177 females and 126 males ranging in age from two months to 88 years. Ninety-nine per cent 300 of 303 of this population had an antibody titre of at least 1:10, whereas 75% had a titre of at least 1:80. Women had a higher geometric mean litre than men P=0.06. This difference between sexes varied according to age and became statistically significant in subjects older than 20 years of age P=0.04. It was found that this difference was attributable to higher antibody litres in women in the 15 to 40 year age group who had previously had children.

Autor: Louise Deschênes, Jean R Joly, Michel Couillard, and Gilles Richer



Documentos relacionados