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Canadian Journal of Gastroenterology - Volume 19 2005, Issue 7, Pages 415-420

Helicobacter Pylori Consensus Update 2004

Departments of Laboratory Medicine & Pathobiology, University of Toronto, Canada

Department of Paediatrics, University of Toronto, Canada

Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada

Copyright © 2005 Hindawi Publishing Corporation. This open-access article is distributed under the terms of the Creative Commons Attribution Non-Commercial License CC BY-NC, which permits reuse, distribution and reproduction of the article, provided that the original work is properly cited and the reuse is restricted to noncommercial purposes.


Bacterial pathogens modulate host cell signal transduction responses to establish infection and cause disease. The purpose of the present summary, first presented at the Canadian Helicobacter Study Group meeting, is to discuss current knowledge of specific Helicobacter pylori factors, including the vacuolating cytotoxin, cytotoxin-associated gene A and the type four secretion system encoded by the cytotoxin-associated gene pathogenicity island and review the host cell signal transduction cascades that they modulate.

Autor: Peter JM Ceponis and Nicola L Jones



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