Preoperative cardiac troponin level is associated with all-cause mortality of liver transplantation recipientsReport as inadecuate




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This study was aimed to evaluate the association between preoperative high-sensitivity cardiac troponin I hs-cTnI level and mortality in patients undergoing liver transplantation LT. From January 2011 to May 2016, preoperative hs-cTnI level was measured in consecutive 487 patients scheduled for LT. Patients with elevated preoperative hs-cTnI were compared with those who had normal level. The primary outcome was all-cause death in follow-up period of 30 days to 1 year after operation. Of the 487 patients, 58 11.9% had elevated preoperative hs-cTnI and 429 88.1% had normal preoperative hs-cTnI. In multivariate analysis, the rate of 1-year mortality and 30-day mortality were higher in elevated preoperative hs-cTnI group hazard ratio HR, 3.69; confidence interval CI 95%, 1.83–7.42; p < 0.001, HR, 6.61; CI, 1.91–22.82; p = 0.003, respectively. After adjustment with inverse probability weighting IPW, the incidence of 1-year mortality and 30-day mortality were higher in elevated group HR, 4.66; CI, 3.56–6.1; p < 0.001, HR, 10.31; CI, 6.39–16.66; p < 0.001, respectively. In conclusion, this study showed that in patients who underwent LT, elevation of preoperative hs-cTnI level was associated with 1-year mortality and 30-day mortality.



Author: Jungchan Park , Seung Hwa Lee , Sangbin Han, Hyun Sook Jee, Suk-Koo Lee, Gyu-Seong Choi, Gaab Soo Kim

Source: http://plos.srce.hr/



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