Structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyesReport as inadecuate




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The location of the peaks of the circumpapillary retinal nerve fiber layer cpRNFL thickness is affected by several ocular parameters. In this study, we have generated equations that can determine the peaks of the cpRNFL. This study was a prospective, observational, cross sectional study of 118 healthy right eyes. The axial length, optic disc tilt, superiortemporal ST- and inferiortemporal IT-peaks of the cpRNFL thickness, and angles of the ST and IT retinal arteries RA and veins RV were determined. The correlations between the location of the ST- and IT-peaks and ocular structural parameters and the sex, body height and weight were calculated. The best fit equations to generate the location of the ST-IT-peaks were determined using corrected-Akaike Information Criteria. The location of the ST-peak was 0.72+0.40 x ST-RA+0.27 x ST-RV+0.14 x height–0.47 x papillo-macular-position–0.11 x disc tilt with a coefficient of correlation of 0.61 P<0.0001. The location of the IT-peak was 21.88+0.53 x IT-RA+0.15 x IT-RV+0.041 x corneal thickness-1.00 x axial length with a coefficient of correlation of 0.59 P<0.0001. The location of ST-IT peaks is determined by different parameters of the ocular structure. These equations allow clinicians to obtain an accurate location of the peaks for a more accurate diagnosis of glaucoma.



Author: Takehiro Yamashita, Ryo Asaoka, Yuya Kii, Hiroto Terasaki, Hiroshi Murata, Taiji Sakamoto

Source: http://plos.srce.hr/



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