Respiratory DNA viruses are undetectable in nasopharyngeal secretions from adenotonsillectomized childrenReportar como inadecuado




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Respiratory viruses are frequently detected in association with chronic tonsillar hypertrophy in the absence of symptoms of acute respiratory infection ARI. The present analysis was done in follow-up to a previous clinical study done by this same group. Nasopharyngeal washes NPWs were obtained from 83 of 120 individuals at variable times post adenotonsillectomy, in the absence of ARI symptoms. A look back at virus detection results in NPWs from the same 83 individuals at the time of tonsillectomy revealed that 73.5% 61-83 were positive for one or more viruses. The overall frequency of respiratory virus detection in post-tonsillectomy NPWs was 58.8%. Rhinovirus RV was the agent most frequently detected, in 38 of 83 subjects 45.8%, followed by enterovirus in 7 8.4%, human metapneumovirus in 6 7.2%, human respiratory syncytial virus in 3 3.6% and human coronavirus in 1 1.2%. Remarkably, there was no detection of adenovirus HAdV or human bocavirus HBoV in asymptomatic individuals in follow-up of adenotonsillectomy. In keeping with persistence of respiratory DNA viruses in human tonsils, tonsillectomy significantly reduces asymptomatic shedding of HAdV and HBoV in NPWs.



Autor: Ronaldo Bragança Martins , Lucas Penna Rocha , Mirela Moreira Prates, Talita Bianca Gagliardi, Balduino Biasoli, Marcelo Junquei

Fuente: http://plos.srce.hr/



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