Osteoporosis in adult patients with atopic dermatitis: A nationwide population-based studyReportar como inadecuado




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The aim of this study was to investigate osteoporosis risk in atopic dermatitis AD patients. This study included patients in the Taiwan National Health Insurance Research dataset. The population-based study included all patients aged 20–49 years who had been diagnosed with AD during 1996–2010. In total, 35,229 age and gender-matched patients without AD in a 1:1 ratio were randomly selected as the non-AD group. Cox proportional-hazards regression and Kaplan–Meier analyses were used to measure the hazard ratios and the cumulative incidences of osteoporosis, respectively. During the follow-up period, 3601.02% AD patients and 1270.36% non-AD patients developed osteoporosis. The overall incidence of osteoporosis was4.72-fold greater in the AD patients compared to the non-AD patients 1.82 vs. 0.24 per 1,000 person-years, respectively after adjusting for potential confounding factors. Osteoporosis risk factors included female gender, age, advanced Charlson Comorbidity Index, depression and use of corticosteroids. The dataset analysis showed that AD was significantly associated with subsequent risk of osteoporosis.



Autor: Ching-Ying Wu , Ying-Yi Lu , Chun-Ching Lu, Yu-Feng Su, Tai-Hsin Tsai, Chieh-Hsin Wu

Fuente: http://plos.srce.hr/



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