Feasibility of Non-Anesthesiologist-Administered Propofol Sedation for Emergency Endoscopic Retrograde CholangiopancreatographyReport as inadecuate

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Gastroenterology Research and Practice - Volume 2015 2015, Article ID 685476, 7 pages -

Research Article

Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan

Department of Gastroenterology, Yuri Kumiai General Hospital, 38 Iego Kawaguchi-aza Yurihonjyo-shi, Akita 015-8511, Japan

Received 17 November 2014; Revised 8 March 2015; Accepted 8 March 2015

Academic Editor: Antoni Castells

Copyright © 2015 Nobuhito Ikeuchi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. The safety of non-anesthesiologist-administered propofol NAAP sedation in emergent endoscopic retrograde cholangiopancreatography ERCP has not been fully clarified. Thus, the aim of this study was to assess the safety of NAAP sedation in emergent ERCP. Materials and Methods. We retrospectively analyzed 182 consecutive patients who had obstructive jaundice and who underwent ERCP under NAAP sedation. The patients were divided into Group A with mild acute cholangitis or without acute cholangitis and Group B moderate or severe acute cholangitis. And technical safety and adverse events were assessed. Results. The adverse events were hypoxia 31 cases, hypotension 26 cases, and bradycardia 2 cases. There was no significant difference in the rate of each adverse event of hypoxia and bradycardia in either group. Although the rate of transient hypotension associated in Group B was higher than that in Group A, it was immediately improved with conservative treatment. Moreover, there were no patients who showed delayed awakening, or who developed other complications. Conclusions. In conclusion, NAAP sedation is feasible even in emergent ERCP. Although some transient adverse events e.g., hypotension were observed, no serious adverse events occurred. Thus, propofol can be used in emergent ERCP but careful monitoring is mandatory.

Author: Nobuhito Ikeuchi, Takao Itoi, Takuji Gotoda, Chika Kusano, Shin Kono, Kentaro Kamada, Takayoshi Tsuchiya, Naoyuki Tominaga,

Source: https://www.hindawi.com/


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