The Relationship between 25 OH D Levels Vitamin D and Bone Mineral Density BMD in a Saudi Population in a Community-Based SettingReportar como inadecuado




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Background

Vitamin D deficiency has been linked to an increased risk of osteoporosis. Vitamin D deficiency has reached high levels in the Saudi population, but there is conflicting evidence both in the Saudi population, and worldwide, regarding the existence of a correlation between these low vitamin D levels and reduced BMD bone mineral density, or osteoporosis.

Objective

The objective of this study was primarily to determine whether there was a correlation between vitamin D deficiency and osteoporosis in the Saudi population. We aimed to investigate whether the high levels of vitamin D deficiency and insufficiency would translate to higher prevalence of osteoporosis, and whether there is a correlation between vitamin D levels and bone mineral density.

Materials and methods

This was a community based cross sectional study conducted in the Family Medicine Clinics at King Faisal Specialist Hospital and Research Centre in Riyadh, Saudi Arabia. Electronic records of 1723 patients were reviewed. Laboratory and radiology results were collected, including vitamin D levels, calcium levels, and bone mineral density scan results.

Results

Among the whole population, 61.5% had moderate to severe vitamin D deficiency with levels less than 50nmol-L. 9.1% of the population had osteoporosis, and 38.6% had osteopenia. Among the whole population, there was no significant correlation between spine or total femoral BMD and serum 25OH D.

Conclusion

Vitamin D deficiency is prevalent in the Saudi population. However, no correlation has been found between vitamin D deficiency and reduced bone mineral density in any age group, in males or females, Saudis or Non-Saudis, in our population in Riyadh, Saudi Arabia.



Autor: Abdullah Alkhenizan , Ahmed Mahmoud, Aneela Hussain, Alia Gabr, Suad Alsoghayer, Abdelmoneim Eldali

Fuente: http://plos.srce.hr/



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