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Canadian Journal of Gastroenterology - Volume 14 2000, Suppl D, Pages 44D-50D

Mini-Review Medizinische Klinik II, Klinikum Aschaffenburg, Am Hasenkopf, Aschaffenburg, Germany

Received 4 February 1999; Accepted 5 February 1999

Copyright © 2000 Hindawi Publishing Corporation. This open-access article is distributed under the terms of the Creative Commons Attribution Non-Commercial License CC BY-NC, which permits reuse, distribution and reproduction of the article, provided that the original work is properly cited and the reuse is restricted to noncommercial purposes.


Primary gastriclymphoma of mucosa-associated lymphoid tissue MALT is a distinctentity with its own histological classification. Epidemiological,histomorphological, molecular biological and experimentaldata clearly underline that infection of the gastric mucosa by Helicobacterpylori plays an important role in both the developmentand progression of MALT lymphoma. Considering the histologicalgrade of malignancy and dissemination stage of the disease asdecisive prognostic factors, and therapeutic determinants, endoscopicbioptical diagnosis and endoscopic ultrasound are of particularimportance. In cases of localized stage 1, low gradelymphoma, eradication of H pylori offers a promising and fascinatingtherapeutic option. Surgical resection, radiotherapy or chemotherapy,and their combination, have proven to be effective treatmentmodalities. There is a need to clarify whether operative orconservative therapeutic strategies should be favoured in the future.

Author: Wolfgang Fischbach



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