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Archives of Industrial Hygiene and Toxicology, Vol.10 No.3 September 1959. -

Addition of UO2++, Sr++ and Pb++ to plasma in concentrations from 12,5-62,5 µg-ml does not influence the prothrombin activity. Mercury ions cause a prolongation of the plasma prothrombin time resulting in a reduction of the prothrombin index values to about 55%. This effect of mercury depends on the concentration of mercury ions and the exposure time. The highest reduction in prothrombin index values was observed at concentrations from 25,0-37,5 µg-ml after 3 hours of exposure. At higher or lower concentrations the effect was less pronounced.

Autor: I. Šimonović - ; Department of Medicine, Medical Faculty, University of Zagreb Krista Kostial - ; Institute for Medical Researc



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