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Journal of Diabetes ResearchVolume 2014 2014, Article ID 320930, 9 pages

Research Article

Endocrinology Post-Graduate Program, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

Cardiology Post-Graduate Program, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil

Department of Internal Medicine, Faculty of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

Cardiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil

Endocrinology Division, Hospital de Clínicas de Porto Alegre, Serviço de Endocrinologia, Rua Ramiro Barcelos 2350, Prédio 12, 4° Andar, 90035-003 Porto Alegre, RS, Brazil

Received 22 June 2014; Accepted 11 August 2014; Published 25 August 2014

Academic Editor: Francesco Chiarelli

Copyright © 2014 M. R. Lopes et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Vitamin D deficiency is frequent among patients with heart failure HF and diabetes, disorders associated with exercise intolerance and muscle weakness. This study aims to search for associations between vitamin D sufficiency and physical function indexes in patients with HF and diabetes. A cross-sectional study of 146 HF patients, 39.7% with diabetes, at a Brazilian tertiary outpatient clinic was performed. Patients underwent clinical evaluation, 6-minute walk test 6 MWT, handgrip strength, physical activity level IPAQ, and biochemical evaluations including serum 25-hydroxyvitamin D. Classification was done according to vitamin D status ≥30 ng-dL, sufficient and presence-absence of diabetes in vitamin sufficient, no diabetes DS-C, , vitamin sufficient, diabetes DS-DM, , vitamin deficient, no diabetes DD-C, , and vitamin deficient, diabetes DD-DM, . Patients age was 55.4 ± 8 yrs; 70.5% had vitamin D deficiency. Clinical characteristics were similar among groups. Total time expended in physical activity was similar among groups . DS-C covered higher distances in the 6 MWT 392 ± 60 m versus DD-DM 309 ± 116 m; . Handgrip strength was similar among groups but tended to lower levels in DD-DM even after being adjusted to physical activity . Vitamin D deficiency can influence physical function in HF diabetic patients.





Autor: M. R. Lopes, Paula A. B. Ribeiro, Priscila Ledur, Gabriela C. Souza, Nadine Clausell, and Beatriz D. Schaan

Fuente: https://www.hindawi.com/



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