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Schizophrenia Research and TreatmentVolume 2012 2012, Article ID 764769, 7 pages

Review Article

Central European Institute of Technology, Masaryk University CEITEC-MU, Kamenice 753-5, 62500 Brno, Czech Republic

Department of Psychiatry, Faculty of Medicine Masaryk University, University Hospital Brno, Jihlavska 20, 62500 Brno, Czech Republic

Received 24 October 2011; Revised 15 February 2012; Accepted 15 February 2012

Academic Editor: Dawn I. Velligan

Copyright © 2012 Radovan Přikryl et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Approximately 80% of patients with the first-episode schizophrenia reach symptomatic remission after antipsychotic therapy. However, within two years most of them relapse, mainly due to low levels of insight into the illness and nonadherence to their oral medication. Therefore, although the formal data available is limited, many experts recommend prescribing long-acting injectable second-generation antipsychotics mostly risperidone or alternatively paliperidone in the early stages of schizophrenia, particularly in patients who have benefited from the original oral molecule in the past and agree to receive long-term injectable treatment. Early application of long-acting injectable second-generation antipsychotics can significantly reduce the risk of relapse in the future and thus improve not only the social and working potential of patients with schizophrenia but also their quality of life.





Autor: Radovan Přikryl, Hana Přikrylová Kučerová, Michaela Vrzalová, and Eva Češková

Fuente: https://www.hindawi.com/



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