Six Year Refractive Change among White Children and Young Adults: Evidence for Significant Increase in Myopia among White UK ChildrenReportar como inadecuado

Six Year Refractive Change among White Children and Young Adults: Evidence for Significant Increase in Myopia among White UK Children - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.


To determine six-year spherical refractive error change among white children and young adults in the UK and evaluate differences in refractive profiles between contemporary Australian children and historical UK data.


Population-based prospective study.


The Northern Ireland Childhood Errors of Refraction NICER study Phase 1 examined 1068 children in two cohorts aged 6–7 years and 12–13 years. Prospective data for six-year follow-up Phase 3 are available for 212 12–13 year olds and 226 18–20 year olds in each cohort respectively.


Cycloplegic refractive error was determined using binocular open-field autorefraction Shin-Nippon NVision-K 5001, cyclopentolate 1%. Participants were defined by spherical equivalent refraction SER as myopic SER ≤-0.50D, emmetropic -0.50D
Main Outcome Measures

Proportion and incidence of myopia.


The proportion of myopes significantly increased between 6–7 years 1.9% and 12–13 years 14.6% p<0.001 but not between 12–13 and 18–20 years 16.4% to 18.6%, p = 0.51. The estimated annual incidence of myopia was 2.2% and 0.7% for the younger and older cohorts respectively. There were significantly more myopic children in the UK at age 12–13 years in the NICER study 16.4% than reported in Australia 4.4% p<0.001. However by 17 years the proportion of myopia neared equivalence in the two populations NICER 18.6%, Australia 17.7%, p = 0.75. The proportion of myopic children aged 12–13 years in the present study 2006–2008 was 16.4%, significantly greater than that reported for children aged 10–16 years in the 1960’s 7.2%, p = 0.01. The proportion of hyperopes in the younger NICER cohort decreased significantly over the six year period from 21.7% to 14.2%, p = 0.04. Hyperopes with SER ≥+3.50D in both NICER age cohorts demonstrated persistent hyperopia.


The incidence and proportion of myopia are relatively low in this contemporary white UK population in comparison to other worldwide studies. The proportion of myopes in the UK has more than doubled over the last 50 years in children aged between 10–16 years and children are becoming myopic at a younger age. Differences between the proportion of myopes in the UK and in Australia apparent at 12–13 years were eliminated by 17 years of age.

Autor: Sara J. McCullough , Lisa O’Donoghue , Kathryn J. Saunders



Documentos relacionados